Mouse (89 sources):
CNS inflammation,
abnormal B cell activation,
abnormal CD4-positive T cell differentiation,
abnormal CD4-positive, alpha-beta intraepithelial T cell morphology,
abnormal CD8-positive, alpha beta T cell morphology,
abnormal CD8-positive, alpha-beta T cell differentiation,
abnormal T cell activation,
abnormal T cell differentiation,
abnormal T cell selection,
abnormal T cell subpopulation ratio,
abnormal bone marrow cell morphology/development,
abnormal digestion,
abnormal double-positive T cell morphology,
abnormal erythropoiesis,
abnormal follicular B cell physiology,
abnormal granulocyte differentiation,
abnormal humoral immune response,
abnormal immune system organ morphology,
abnormal intraepithelial T cell morphology,
abnormal intraepithelial T cell number,
abnormal long bone metaphysis morphology,
abnormal lymphopoiesis,
abnormal memory T cell number,
abnormal osteoclast morphology,
abnormal osteoclast physiology,
abnormal positive T cell selection,
abnormal response to infection,
abnormal thymocyte activation,
absent T cells,
arrested T cell differentiation,
decreased B cell proliferation,
decreased B-1a cell number,
decreased B-1b cell number,
decreased B-2 B cell number,
decreased CD4-positive, alpha beta T cell number,
decreased CD4-positive, alpha-beta memory T cell number,
decreased CD8-positive, alpha-beta memory T cell number,
decreased CD8-positive, naive alpha-beta T cell number,
decreased DN4 thymocyte number,
decreased NK T cell number,
decreased T cell proliferation,
decreased alpha-beta T cell number,
decreased central memory CD8 positive, alpha-beta T cell number,
decreased cytotoxic T cell cytolysis,
decreased double-positive T cell number,
decreased effector memory CD4-positive, alpha-beta T cell number,
decreased follicular B cell number,
decreased gamma-delta intraepithelial T cell number,
decreased mast cell degranulation,
decreased mature B cell number,
decreased memory B cell number,
decreased memory T cell number,
decreased oligodendrocyte number,
decreased single-positive T cell number,
decreased susceptibility to type I hypersensitivity reaction,
decreased systemic arterial systolic blood pressure,
decreased thymocyte number,
enlarged lymph nodes,
hematopoietic system phenotype,
immune system phenotype,
increased B-1 B cell number,
increased B-1b cell number,
increased CD8-positive, alpha-beta T cell number,
increased DN3 thymocyte number,
increased IgG2a level,
increased NK cell number,
increased T cell apoptosis,
increased alpha-beta T cell number,
increased anti-double stranded DNA antibody level,
increased central memory CD4-positive, alpha-beta T cell number,
increased central memory CD8 positive, alpha-beta T cell number,
increased dendritic cell number,
increased double-negative T cell number,
increased effector memory CD4-positive, alpha-beta T cell number,
increased effector memory CD8-positive, alpha-beta T cell number,
increased memory T cell number,
increased neutrophil cell number,
increased plasma cell number,
increased plasmacytoid dendritic cell number,
increased single-positive T cell number,
increased spleen red pulp amount,
increased spleen white pulp amount,
increased susceptibility to Herpesvirales infection,
increased susceptibility to autoimmune disorder,
increased transitional stage B cell number,
lethality at weaning, incomplete penetrance,
no abnormal phenotype detected,
premature death,
spleen hyperplasia
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