| Monarch Ortholog Phenotypes
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Human (16 sources):
Brain atrophy,
Cardiomyopathy,
Cataract,
Cerebral atrophy,
Delayed CNS myelination,
Encephalopathy,
Feeding difficulties,
Global developmental delay,
High pitched voice,
Intrauterine growth retardation,
[+]
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Mouse (14 sources):
abnormal breathing pattern,
abnormal heart development,
abnormal myocardial fiber morphology,
abnormal sarcomere morphology,
absent Z line,
cardiovascular system phenotype,
decreased body size,
decreased male germ cell number,
perinatal lethality, incomplete penetrance,
postnatal lethality, complete penetrance,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.