| Monarch Ortholog Phenotypes
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Human (10 sources):
Cafe-au-lait spot,
Decreased body weight,
Dilated cardiomyopathy,
Gastroesophageal reflux,
Global developmental delay,
Intrauterine growth retardation,
Microcephaly,
Recurrent infections,
Reduced subcutaneous adipose tissue,
Short stature
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Mouse (8 sources):
abnormal grip strength,
abnormal inner cell mass proliferation,
decreased exploration in new environment,
decreased grip strength,
embryonic lethality between implantation and somite formation, complete penetrance,
embryonic lethality prior to organogenesis,
increased anxiety-related response,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.