plcb4 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (196)

Interactants (4)

XB-GENEPAGE-1010442

Gene Symbol: plcb4 Gene Name: phospholipase C beta 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: plcb4 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (44 sources): Abnormal pinna morphology, Abnormality of the crus of the helix, Abnormality of the temporomandibular joint, Ankylosis, Aplasia/Hypoplasia of the external ear, Apnea, Bifid uvula, Cleft at the superior portion of the pinna, Cleft helix, Cleft palate, Dental crowding, Dental malocclusion, Difficulty in tongue movements, Facial asymmetry, Feeding difficulties, Full cheeks, Generalized hypotonia, Global developmental delay, Glossoptosis, Hamartoma of tongue, Hearing impairment, Hypoplastic superior helix, Low-set ears, Low-set, posteriorly rotated ears, Macrocephaly, Mandibular condyle aplasia, Mandibular condyle hypoplasia, Microglossia, Micrognathia, Narrow mouth, Obstructive sleep apnea, Overfolding of the superior helices, Periauricular skin pits, Posteriorly rotated ears, Preauricular skin tag, Ptosis, Question mark ear, Respiratory distress, Round face, Short mandibular rami, Snoring, Speech articulation difficulties, Vein of Galen aneurysmal malformation, obsolete External ear malformation [+]
Mouse (27 sources): abnormal Purkinje cell innervation, abnormal adipose tissue amount, abnormal bone mineralization, abnormal cerebellar foliation, abnormal cerebellum external granule cell layer morphology, abnormal exploration in a new environment, abnormal grip strength, abnormal lean body mass, abnormal locomotor behavior, abnormal locomotor coordination, abnormal rod electrophysiology, decreased body size, decreased exploration in new environment, decreased heart weight, decreased locomotor activity, enlarged gallbladder, hydrometra, increased bone mineral content, increased grip strength, increased lean body mass, muscle phenotype, postnatal lethality, incomplete penetrance, reduced long term depression, short stride length, skeleton phenotype, small cerebellum, small superior vagus ganglion [+]
View all ortholog results at Monarch