dock1 Phenotypes

XB-GENEPAGE-1010792

Gene Symbol: dock1 Gene Name: dedicator of cytokinesis 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: dock1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources): abnormal diaphragm morphology, abnormal heart right ventricle outflow tract morphology, abnormal intercostal muscle morphology, abnormal muscle development, abnormal myogenesis, abnormal vascular endothelial cell migration, abnormal vasculogenesis, atrioventricular septal defect, decreased birth body size, decreased skeletal muscle fiber diameter, decreased skeletal muscle mass, endocrine/exocrine gland phenotype, lethality at weaning, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, prenatal lethality, complete penetrance, thick mitral valve cusps, thin diaphragm muscle [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (17 sources): abnormal diaphragm morphology, abnormal heart right ventricle outflow tract morphology, abnormal intercostal muscle morphology, abnormal muscle development, abnormal myogenesis, abnormal vascular endothelial cell migration, abnormal vasculogenesis, atrioventricular septal defect, decreased birth body size, decreased skeletal muscle fiber diameter, [+]