| Monarch Ortholog Phenotypes
|
|
Human (4 sources):
Intention tremor,
Kinetic tremor,
Postural tremor,
Tongue tremor
|
Mouse (24 sources):
abnormal cervical axis morphology,
abnormal embryonic tissue morphology,
abnormal grip strength,
abnormal oligodendrocyte apoptosis,
abnormal rostral-caudal axis patterning,
abnormal spinal cord dorsal column morphology,
abnormal spinal cord white matter morphology,
absent mesoderm,
decreased body size,
decreased fasting circulating glucose level,
decreased heart weight,
decreased lean body mass,
decreased thigmotaxis,
embryonic growth arrest,
embryonic growth retardation,
embryonic lethality between implantation and somite formation, complete penetrance,
embryonic lethality during organogenesis, complete penetrance,
failure of chorioallantoic fusion,
hindlimb paralysis,
incomplete somite formation,
increased bone mineral content,
increased grip strength,
open neural tube,
prenatal lethality, complete penetrance
[+]
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.