zc3h12a Phenotypes

Phenotypes

XB-GENEPAGE-1219175

Gene Symbol: zc3h12a Gene Name: zinc finger CCCH-type containing 12A

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: zc3h12a assayed (7 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (24 sources): abnormal acute inflammation, abnormal circulating chemokine level, abnormal class switch recombination, abnormal proerythroblast morphology, decreased hematocrit, decreased hemoglobin content, enlarged lymph nodes, granulomatous inflammation, increased IgG1 level, increased IgG2a level, increased IgG2b level, increased IgG3 level, increased anti-double stranded DNA antibody level, increased anti-nuclear antigen antibody level, increased circulating tumor necrosis factor level, increased interferon-gamma secretion, increased interleukin-1 beta secretion, increased interleukin-12b secretion, increased interleukin-6 secretion, increased memory T cell number, increased plasma cell number, increased tumor necrosis factor secretion, premature death, preweaning lethality, incomplete penetrance [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (24 sources): abnormal acute inflammation, abnormal circulating chemokine level, abnormal class switch recombination, abnormal proerythroblast morphology, decreased hematocrit, decreased hemoglobin content, enlarged lymph nodes, granulomatous inflammation, increased IgG1 level, increased IgG2a level, [+]