| Monarch Ortholog Phenotypes
|
Human (25 sources):
Anisocytosis,
Atelectasis,
Axial hypotonia,
Brain atrophy,
Cardiomegaly,
Chronic hemolytic anemia,
Decreased mean corpuscular volume,
Diarrhea,
Dystonia,
Elliptocytosis,
Failure to thrive,
Feeding difficulties,
Global developmental delay,
Hepatocellular necrosis,
Hepatomegaly,
Hypoplasia of the corpus callosum,
Irritability,
Poikilocytosis,
Recurrent infections,
Respiratory insufficiency,
Reticulocytosis,
Seizure,
Strabismus,
Tachypnea,
Tetraplegia
[+]
|
|
Mouse (3 sources):
abnormal trophoblast layer morphology,
embryonic lethality during organogenesis, complete penetrance,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.