slc6a4 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-22062971

Gene Symbol: slc6a4 Gene Name: solute carrier family 6 (neurotransmitter transporter), member 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: slc6a4 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (44 sources): abnormal action potential, abnormal active avoidance behavior, abnormal anxiety-related response, abnormal barrel cortex morphology, abnormal crypts of Lieberkuhn morphology, abnormal enteric neuron morphology, abnormal gastrointestinal motility, abnormal intestinal peristalsis, abnormal intestinal transit time, abnormal neurite morphology, abnormal neuron physiology, abnormal neurotransmitter uptake, abnormal response to new environment, abnormal response to novel object, abnormal response to social novelty, abnormal serotonergic neuron morphology, abnormal sleep pattern, abnormal small intestinal crypt cell proliferation, abnormal small intestinal transit time, abnormal small intestine crypts of Lieberkuhn morphology, abnormal social investigation, abnormal thermal nociception, behavioral despair, cardiac fibrosis, decreased cardiac muscle contractility, decreased exploration in new environment, decreased locomotor activity, decreased physiological sensitivity to xenobiotic, decreased serotonin level, decreased small intestinal villus height, decreased vocalization, enhanced behavioral response to xenobiotic, enhanced conditioned place preference behavior, growth/size/body region phenotype, heart valve hyperplasia, impaired behavioral response to xenobiotic, increased brain weight, increased physiological sensitivity to xenobiotic, increased right ventricle systolic pressure, increased serotonin level, increased startle reflex, no abnormal phenotype detected, postnatal lethality, incomplete penetrance, social withdrawal [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (44 sources): abnormal action potential, abnormal active avoidance behavior, abnormal anxiety-related response, abnormal barrel cortex morphology, abnormal crypts of Lieberkuhn morphology, abnormal enteric neuron morphology, abnormal gastrointestinal motility, abnormal intestinal peristalsis, abnormal intestinal transit time, abnormal neurite morphology, [+]