pdp1 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (111)

Interactants (26)

XB-GENEPAGE-481256

Gene Symbol: pdp1 Gene Name: pyruvate dehydrogenase phosphatase catalytic subunit 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pdp1 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (10 sources): Decreased activity of the pyruvate dehydrogenase complex, Dysphagia, Gait ataxia, Generalized hypotonia, Global developmental delay, Hypotonia, Intellectual disability, Lactic acidosis, Nystagmus, Seizure
Mouse (13 sources): abnormal blood urea nitrogen level, abnormal circulating alanine transaminase level, abnormal cued conditioning behavior, abnormal freezing behavior, abnormal mean corpuscular volume, decreased circulating alanine transaminase level, decreased freezing behavior, decreased grip strength, impaired cued conditioning behavior, improved glucose tolerance, increased fasting circulating glucose level, increased heart weight, increased mean corpuscular hemoglobin [+]
View all ortholog results at Monarch