osr2 Phenotypes

Phenotypes

XB-GENEPAGE-481906

Gene Symbol: osr2 Gene Name: odd-skipped related transcription factor 2

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
absent lung bud (5 sources), abnormal development of foregut (3 sources), abnormal development of lung (2 sources), abnormal development of esophagus (1 source), abnormal development of trachea (1 source), abnormal foregut morphology (1 source), decreased size of the stomach (1 source), increased apoptosis in embryo (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: osr2 manipulated (29 sources), osr2 assayed (2 sources)
Computed annotations: osr2 assayed (22 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + Mmu.osr1-GR + osr1 MO + osr2 MO (10 sources), Xtr Wt + osr1 MO + osr2 MO (8 sources), Xtr Wt + osr1 MO + osr2 MO (8 sources), Xtr Wt + osr1 MO + osr2 MO + BIO (2 sources), Xtr Wt + osr1 MO + osr2 MO + RA (2 sources), Xtr Wt + osr1 MO + osr2 MO + BIO + RA (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (14 sources): abnormal eye development, abnormal eyelid fusion, abnormal lower incisor morphology, abnormal tooth development, abnormal tympanic ring morphology, craniofacial phenotype, decreased tympanic ring size, eyelids open at birth, failure of eyelid fusion, fused synovial joints, hearing/vestibular/ear phenotype, neonatal lethality, complete penetrance, no abnormal phenotype detected, palatal shelves fail to meet at midline [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (14 sources): abnormal eye development, abnormal eyelid fusion, abnormal lower incisor morphology, abnormal tooth development, abnormal tympanic ring morphology, craniofacial phenotype, decreased tympanic ring size, eyelids open at birth, failure of eyelid fusion, fused synovial joints, [+]