pdgfa Phenotypes

Phenotypes

XB-GENEPAGE-484494

Gene Symbol: pdgfa Gene Name: platelet derived growth factor subunit A

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal cell adhesion (1 source), abnormal mesoderm morphology (1 source), decreased cell adhesion in mesodermal cell (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pdgfa assayed (8 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + BCR removal + PDGFA MO (0 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (19 sources): abnormal epididymis epithelium morphology, abnormal epididymis morphology, abnormal pulmonary alveolar parenchyma morphology, abnormal pulmonary elastic fiber morphology, abnormal pulmonary interalveolar septum morphology, absent pulmonary alveoli, arrest of spermatogenesis, decreased body size, decreased fetal size, decreased small intestinal villus number, embryonic lethality during organogenesis, incomplete penetrance, enlarged thoracic cavity, fetal growth retardation, impaired lung alveolus development, lung hemorrhage, postnatal lethality, incomplete penetrance, premature death, respiratory system phenotype, thick ventricular wall [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (19 sources): abnormal epididymis epithelium morphology, abnormal epididymis morphology, abnormal pulmonary alveolar parenchyma morphology, abnormal pulmonary elastic fiber morphology, abnormal pulmonary interalveolar septum morphology, absent pulmonary alveoli, arrest of spermatogenesis, decreased body size, decreased fetal size, decreased small intestinal villus number, [+]