dusp22 Phenotypes

Phenotypes

XB-GENEPAGE-486790

Gene Symbol: dusp22 Gene Name: dual specificity phosphatase 22

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: dusp22 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (20 sources): abnormal B cell activation, abnormal T cell activation, abnormal cytokine level, abnormal glomerular mesangium morphology, abnormal renal glomerulus morphology, decreased B cell proliferation, decreased IgG3 level, increased T cell proliferation, increased circulating interferon-gamma level, increased circulating interleukin-17 level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased interferon-gamma secretion, increased interleukin-17 secretion, increased interleukin-2 secretion, increased interleukin-4 secretion, increased renal glomerulus lobularity, increased spleen white pulp amount, increased susceptibility to autoimmune disorder, increased susceptibility to experimental autoimmune encephalomyelitis [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (20 sources): abnormal B cell activation, abnormal T cell activation, abnormal cytokine level, abnormal glomerular mesangium morphology, abnormal renal glomerulus morphology, decreased B cell proliferation, decreased IgG3 level, increased T cell proliferation, increased circulating interferon-gamma level, increased circulating interleukin-17 level, [+]