| Monarch Ortholog Phenotypes
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Human (2 sources):
Drug-induced agranulocytosis,
Oral ulcer
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Mouse (40 sources):
abnormal apoptosis,
abnormal embryo size,
abnormal female meiosis,
abnormal fertility/fecundity,
abnormal gametogenesis,
abnormal imprinting,
abnormal intestinal goblet cell morphology,
abnormal liquid preference,
abnormal locomotor behavior,
abnormal neuron physiology,
arrest of male meiosis,
decreased IgG1 level,
decreased anxiety-related response,
decreased embryo size,
decreased exploration in new environment,
decreased interleukin-13 secretion,
decreased interleukin-4 secretion,
decreased interleukin-5 secretion,
decreased litter size,
decreased locomotor activity,
decreased male germ cell number,
decreased oocyte number,
decreased trophoblast giant cell number,
decreased vertical activity,
embryonic growth arrest,
embryonic lethality during organogenesis, complete penetrance,
embryonic lethality prior to tooth bud stage,
enhanced behavioral response to xenobiotic,
impaired behavioral response to xenobiotic,
increased IgG2a level,
increased interferon-gamma secretion,
increased interleukin-17 secretion,
increased lean body mass,
increased susceptibility to parasitic infection,
induced hyperactivity,
nervous system phenotype,
no abnormal phenotype detected,
open neural tube,
prenatal lethality, complete penetrance,
preweaning lethality, complete penetrance
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View all ortholog results at Monarch
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These phenotypes are associated with this gene with a has phenotype relation via Monarch.