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XB-GENEPAGE-487535
nphp4.2 nephronophthisis 4, gene 2
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal cilium assembly (3 sources), abnormally decreased number of ciliated cell (3 sources), obsolete decreased cilium motility in ciliated epidermal cell (2 sources) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: nphp4.2 manipulated (5 sources) |
| Computed annotations: nphp4.2 assayed (3 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + nphp4 MO (3 sources), Xla Wt + nphp4 MO (1 source), Xla Wt + nphp4 MO (1 source), Xla Wt + nphp4 MO (1 source), Xla Wt + nphp4 MO (1 source), Xla Wt + nphp4 MO (1 source), Xla Wt + nphp4 MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (29 sources): Abnormality of bone mineral density, Abnormality of retinal pigmentation, Amblyopia, Anemia, Ataxia, Cataract, Chronic kidney disease, Cone-shaped epiphysis, Congenital hepatic fibrosis, Global developmental delay, [+] |
| Mouse (15 sources): abnormal photoreceptor outer segment morphology, abnormal retina apoptosis, abnormal retina blood vessel morphology, abnormal retina outer nuclear layer morphology, abnormal retina outer plexiform layer morphology, asthenozoospermia, decreased retina inner nuclear layer thickness, impaired fertilization, renal/urinary system phenotype, reproductive system phenotype, [+] |
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View all ortholog results at Monarch |