prkcq Phenotypes

Summary

Expression

Phenotypes

Gene Literature (0)

XB-GENEPAGE-487642

Gene Symbol: prkcq Gene Name: protein kinase C theta

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: prkcq assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (43 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal T cell activation, abnormal T-helper 1 cell differentiation, abnormal T-helper 2 physiology, abnormal adipocyte glucose uptake, abnormal choroid vasculature morphology, abnormal effector T cell morphology, abnormal endplate potential, abnormal eye electrophysiology, abnormal muscle cell glucose uptake, abnormal nervous system development, abnormal neuromuscular synapse morphology, abnormal photoreceptor outer segment morphology, abnormal platelet activation, abnormal platelet dense granule physiology, abnormal positive T cell selection, abnormal response to infection, abnormal retina blood vessel morphology, abnormal retina cone cell morphology, abnormal retina cone cell outer segment morphology, decreased CD4-positive, alpha beta T cell number, decreased DN1 thymic pro-T cell number, decreased NK T cell number, decreased T cell apoptosis, decreased T cell proliferation, decreased airway responsiveness, decreased eye pigmentation, decreased interferon-gamma secretion, decreased interleukin-13 secretion, decreased interleukin-17 secretion, decreased interleukin-2 secretion, decreased interleukin-4 secretion, decreased interleukin-5 secretion, decreased physiological sensitivity to xenobiotic, decreased splenocyte proliferation, decreased susceptibility to experimental autoimmune encephalomyelitis, immune system phenotype, impaired humoral immune response, increased T cell apoptosis, increased insulin sensitivity, increased platelet aggregation, retina pigment epithelium atrophy, serous retina detachment [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (43 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal T cell activation, abnormal T-helper 1 cell differentiation, abnormal T-helper 2 physiology, abnormal adipocyte glucose uptake, abnormal choroid vasculature morphology, abnormal effector T cell morphology, abnormal endplate potential, abnormal eye electrophysiology, abnormal muscle cell glucose uptake, [+]