| Monarch Ortholog Phenotypes
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Human (3 sources):
Elevated diastolic blood pressure,
Elevated mean arterial pressure,
Elevated systolic blood pressure
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Mouse (24 sources):
abnormal aorta tunica adventitia morphology,
abnormal aorta tunica media morphology,
abnormal aorta wall morphology,
abnormal heart weight,
abnormal kidney morphology,
abnormal kidney weight,
abnormal renal tubule morphology,
abnormal thoracic aorta morphology,
abnormal thromboxane level,
abnormal thymus morphology,
decreased kidney weight,
decreased mean corpuscular volume,
decreased prostaglandin level,
dilated renal glomerular capsule,
enlarged lymph nodes,
enlarged thymus,
increased brain size,
increased circulating creatinine level,
increased heart weight,
increased prostaglandin level,
increased systemic arterial blood pressure,
kidney vascular congestion,
renal necrosis,
small kidney
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.