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Summary Expression Phenotypes Gene Literature (7) GO Terms (10) Nucleotides (314) Proteins (56) Interactants (152) Wiki
XB-GENEPAGE-491635

sesn1     sestrin 1

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: sesn1 assayed (12 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (11 sources): abnormal class switch recombination, abnormal effector T cell number, decreased prepulse inhibition, increased NK T cell number, increased T cell proliferation, increased aggression, increased interferon-gamma secretion, increased interleukin-2 secretion, increased myeloid cell number, increased single-positive T cell number, [+]