gdf15 Phenotypes

Phenotypes

XB-GENEPAGE-5714901

Gene Symbol: gdf15 Gene Name: growth differentiation factor 15

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gdf15 assayed (9 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (25 sources): abnormal L4 dorsal root ganglion morphology, abnormal L5 dorsal root ganglion morphology, abnormal basal metabolism, abnormal kidney morphology, decreased bleeding time, decreased energy expenditure, decreased lean body mass, decreased locomotor activity, decreased motor neuron number, decreased neuron number, decreased sensory neuron number, homeostasis/metabolism phenotype, increased fluid intake, increased food intake, increased inguinal fat pad weight, increased kidney weight, increased mesenteric fat pad weight, increased myocardial infarct size, increased platelet aggregation, increased retroperitoneal fat pad weight, increased sensitivity to induced morbidity/mortality, increased susceptibility to induced thrombosis, increased total body fat amount, increased white adipose tissue amount, prolonged PQ interval [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (25 sources): abnormal L4 dorsal root ganglion morphology, abnormal L5 dorsal root ganglion morphology, abnormal basal metabolism, abnormal kidney morphology, decreased bleeding time, decreased energy expenditure, decreased lean body mass, decreased locomotor activity, decreased motor neuron number, decreased neuron number, [+]