Cataract, Cerebral ischemia, Cutis marmorata, Dental crowding, Depression, Disproportionate tall stature, Ectopia lentis, Elevated circulating hepatic transaminase concentration, Esophageal varix, Failure to thrive, Gastrointestinal hemorrhage, Generalized osteoporosis, Genu valgum, Glaucoma, Global developmental delay, Hemiplegia/hemiparesis, Hepatic steatosis, Hepatomegaly, Hernia, High palate, Homocystinuria, Hyperhomocystinemia, Hypermethioninemia, Hypertension, Hypopigmentation of the skin, Intellectual disability, Intracranial hemorrhage, Joint stiffness, Kyphoscoliosis, Kyphosis, Lens subluxation, Limitation of joint mobility, Methioninuria, Mitral valve prolapse, Myocardial infarction, Myopia, Optic atrophy, Osteoporosis, Pancreatitis, Pectus carinatum, Pectus excavatum, Personality disorder, Psychosis, Pulmonary embolism, Recurrent fractures, Retinal detachment, Scoliosis, Seizure, Sparse scalp hair, Stroke, Subcutaneous hemorrhage, Tall stature, Thromboembolism, Urticaria, Venous thrombosis, Visual impairment

abnormal interleukin level, abnormal keratinocyte differentiation, abnormal limb morphology, abnormal lung development, abnormal maternal decidual layer morphology, abnormal ovarian follicle number, abnormal pericyte morphology, abnormal placenta junctional zone morphology, abnormal placenta labyrinth morphology, abnormal pregnancy, abnormal retina blood vessel morphology, abnormal retina blood vessel pattern, abnormal retina vasculature morphology, abnormal tail morphology, abnormal tumor necrosis factor level, abnormal uterine environment, abnormal uterus weight, abnormal vascular endothelial cell physiology, abnormal vasodilation, abnormal venule morphology, abnormal vitreous body morphology, behavior/neurological phenotype, blood vessel congestion, decreased body size, decreased litter size, decreased placenta weight, delayed eyelid opening, delayed kidney development, enlarged sebaceous gland, enlarged spinous cells, hemosiderosis, increased astrocyte number, increased circulating homocysteine level, increased circulating progesterone level, increased hair follicle number, increased hepatocyte apoptosis, increased vascular permeability, integument phenotype, microvesicular hepatic steatosis, oxidative stress, pale liver, pointed snout, postnatal lethality, incomplete penetrance, premature death, prolonged metestrus, retina gliosis, retina ischemia, retina microaneurysm, short diestrus, short estrous cycle, short estrus, thin dermal layer, thin hypodermis