mpzl3 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (1)

XB-GENEPAGE-5768598

Gene Symbol: mpzl3 Gene Name: myelin protein zero like 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: mpzl3 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (52 sources): abnormal coat appearance, abnormal dermis papillary layer morphology, abnormal dermis reticular layer morphology, abnormal epidermis stratum corneum morphology, abnormal epididymal fat pad morphology, abnormal gonadal fat pad morphology, abnormal hair follicle melanocyte morphology, abnormal hair follicle morphology, abnormal hair follicle regression, abnormal maternal nurturing, abnormal muscle contractility, abnormal myocardial fiber morphology, abnormal sebaceous gland morphology, abnormal sebaceous gland physiology, abnormal sebaceous lipid secretion, acanthosis, decreased body fat mass, decreased body length, decreased bone mineral density of femur, decreased circulating free fatty acids level, decreased circulating phospholipid level, decreased hair follicle number, decreased liver triglyceride level, decreased susceptibility to diet-induced obesity, decreased susceptibility to hepatic steatosis, decreased white fat cell size, dermatitis, dilated hair follicles, dilated piliary canal, disheveled coat, enlarged sebaceous gland, epidermal hyperplasia, greasy coat, hair follicle degeneration, hypergranulosis, improved glucose tolerance, increased basal metabolism, increased bone marrow cell number, increased energy expenditure, increased lean body mass, increased oxygen consumption, increased respiratory quotient, increased sebum secretion, loss of vibrissae, myocardial fiber degeneration, pigment incontinence, rough coat, sebaceous gland hypertrophy, skin fibrosis, skin lesions, thick dermal layer, underdeveloped hair follicles [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (52 sources): abnormal coat appearance, abnormal dermis papillary layer morphology, abnormal dermis reticular layer morphology, abnormal epidermis stratum corneum morphology, abnormal epididymal fat pad morphology, abnormal gonadal fat pad morphology, abnormal hair follicle melanocyte morphology, abnormal hair follicle morphology, abnormal hair follicle regression, abnormal maternal nurturing, [+]