spns2 Phenotypes

Phenotypes

XB-GENEPAGE-5793582

Gene Symbol: spns2 Gene Name: spinster homolog 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: spns2 assayed (23 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (43 sources): abnormal corneal stroma morphology, abnormal effector T cell morphology, abnormal eye pigmentation, abnormal eye size, abnormal humoral immune response, abnormal iridocorneal angle, abnormal mature B cell number, abnormal mean corpuscular hemoglobin, abnormal thymus morphology, absent pinna reflex, decreased B-1 B cell number, decreased CD4-positive, alpha beta T cell number, decreased IgG1 level, decreased bone mineral content, decreased circulating glucose level, decreased follicular B cell number, decreased immature B cell number, decreased lumbar vertebrae number, decreased mature B cell number, decreased single-positive T cell number, decreased sphingosine level, decreased survivor rate, decreased thymocyte number, decreased transitional stage T1 B cell number, excessive tearing, eye opacity, eyelids fail to open, eyelids open at birth, growth/size/body region phenotype, immune system phenotype, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased NK T cell number, increased NK cell number, increased bone mineral content, increased bone strength, increased granulocyte number, increased incidence of corneal inflammation, increased mean corpuscular hemoglobin, increased sacral vertebrae number, increased single-positive T cell number, trunk curl, vision/eye phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (43 sources): abnormal corneal stroma morphology, abnormal effector T cell morphology, abnormal eye pigmentation, abnormal eye size, abnormal humoral immune response, abnormal iridocorneal angle, abnormal mature B cell number, abnormal mean corpuscular hemoglobin, abnormal thymus morphology, absent pinna reflex, [+]