| Monarch Ortholog Phenotypes
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Human (45 sources):
Abnormal cortical bone morphology,
Abnormal fingernail morphology,
Abnormal hair pattern,
Abnormal hair quantity,
Abnormality of bone marrow cell morphology,
Abnormality of epiphysis morphology,
Acne,
Anemia,
Arthralgia,
Arthritis,
Avascular necrosis,
Bone pain,
Cerebral palsy,
Clubbing,
Clubbing of toes,
Coarse facial features,
Cutis gyrata of scalp,
Edema,
Elevated circulating growth hormone concentration,
Gastrointestinal hemorrhage,
Genu varum,
Gynecomastia,
Hematuria,
Hepatomegaly,
Hyperhidrosis,
Hyperostosis,
Impaired temperature sensation,
Joint swelling,
Limitation of joint mobility,
Malabsorption,
Neoplasm of the lung,
Neoplasm of the skin,
Osteolysis,
Osteomyelitis,
Osteoporosis,
Palmoplantar keratoderma,
Peptic ulcer,
Periostosis,
Ptosis,
Scoliosis,
Seborrheic dermatitis,
Small hand,
Splenomegaly,
Thickened skin,
obsolete Eczematoid dermatitis
[+]
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Mouse (4 sources):
abnormal prostaglandin level,
dilated heart left ventricle,
neonatal lethality, complete penetrance,
postnatal lethality, complete penetrance
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.