mtss1.2 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-5824174

Gene Symbol: mtss1.2 Gene Name: metastasis suppressor 1, gene 2

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal incomplete closing of the anterior neural fold (3 sources), abnormal anterior-posterior axis morphology (2 sources), abnormal neural tube closure (2 sources), abnormal apical constriction (1 source), abnormal establishment of cell polarity (1 source), abnormal incomplete closing of the neural tube (1 source), abnormal opening of the anterior neural tube (1 source), decreased size of the actin cytoskeleton (1 source), decreased size of the anterior neural fold (1 source)

Anatomical Phenotypes

Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.

abnormal incomplete closing of the anterior neural fold (3 sources), abnormal anterior-posterior axis morphology (2 sources), abnormal neural tube closure (2 sources), abnormal apical constriction (1 source), abnormal establishment of cell polarity (1 source), abnormal incomplete closing of the neural tube (1 source), abnormal opening of the anterior neural tube (1 source), decreased size of the actin cytoskeleton (1 source), decreased size of the anterior neural fold (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: mtss1.2 manipulated (3 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + mtss1.2 MO (7 sources), Xla Wt + mtss1.2 MO (3 sources), Xla Wt + daam1 MO + mtss1.2 MO (1 source), Xla Wt + mtss1.2 MO (1 source), Xla Wt + mtss1.2 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (14 sources): abnormal cell adhesion, abnormal cell morphology, decreased bone mineral content, decreased immature B cell number, dilated renal tubules, impaired fibroblast cell migration, increased B cell derived lymphoma incidence, increased circulating alkaline phosphatase level, increased fluid intake, increased kidney cell proliferation, increased pre-B cell number, increased renal glomerulus basement membrane thickness, kidney degeneration, premature death [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (14 sources): abnormal cell adhesion, abnormal cell morphology, decreased bone mineral content, decreased immature B cell number, dilated renal tubules, impaired fibroblast cell migration, increased B cell derived lymphoma incidence, increased circulating alkaline phosphatase level, increased fluid intake, increased kidney cell proliferation, [+]