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XB-GENEPAGE-5963240
cd40 CD40 molecule, TNF receptor superfamily member 5
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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Computed annotations: cd40 assayed (3 sources) |
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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Human (10 sources): Absence of lymph node germinal center, Decreased circulating IgA level, Decreased circulating IgE, Decreased circulating IgG level, Immunodeficiency, Impaired Ig class switch recombination, Impaired memory B cell generation, Increased circulating IgM level, Neutropenia, Recurrent bacterial infections |
Mouse (21 sources): abnormal dendritic cell physiology, abnormal humoral immune response, abnormal lymph node germinal center morphology, abnormal response to transplant, absent germinal center B cells, absent spleen germinal center, decreased IgG1 level, decreased IgG2a level, decreased IgG2b level, decreased IgG3 level, [+] |
View all ortholog results at Monarch |