pbrm1 Phenotypes

Phenotypes

XB-GENEPAGE-6450125

Gene Symbol: pbrm1 Gene Name: polybromo 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pbrm1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (15 sources): abnormal T-helper 2 cell differentiation, abnormal kidney morphology, abnormal placenta labyrinth morphology, abnormal spongiotrophoblast layer morphology, abnormal trophoblast giant cell morphology, decreased T cell proliferation, decreased grip strength, immune system phenotype, increased interleukin-10 secretion, increased interleukin-4 secretion, lethality throughout fetal growth and development, complete penetrance, preweaning lethality, complete penetrance, small liver, small lung, ventricular hypoplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (15 sources): abnormal T-helper 2 cell differentiation, abnormal kidney morphology, abnormal placenta labyrinth morphology, abnormal spongiotrophoblast layer morphology, abnormal trophoblast giant cell morphology, decreased T cell proliferation, decreased grip strength, immune system phenotype, increased interleukin-10 secretion, increased interleukin-4 secretion, [+]