| Monarch Ortholog Phenotypes
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Human (43 sources):
Abnormality of epiphysis morphology,
Abnormality of hair pigmentation,
Abnormality of the dentition,
Arachnodactyly,
Blue sclerae,
Bruising susceptibility,
Camptodactyly,
Cleft palate,
Conductive hearing impairment,
Corneal dystrophy,
Corneal erosion,
Corneal scarring,
Decreased corneal thickness,
Flat cornea,
Gait disturbance,
Glaucoma,
Hallux valgus,
Hearing impairment,
Hernia,
High myopia,
Hip dysplasia,
Hyperextensible skin,
Increased susceptibility to fractures,
Joint hypermobility,
Keratoconus,
Keratoglobus,
Megalocornea,
Mitral valve prolapse,
Myalgia,
Myopia,
Neonatal hypotonia,
Osteoporosis,
Pes planus,
Pulmonic stenosis,
Recurrent fractures,
Retinal detachment,
Sclerocornea,
Scoliosis,
Sensorineural hearing impairment,
Soft skin,
Umbilical hernia,
Visual loss,
obsolete Joint hyperflexibility
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Mouse (14 sources):
abnormal anxiety-related response,
abnormal exploration in a new environment,
abnormal locomotor activation,
abnormal osteoblast morphology,
decreased bone mineral content,
decreased bone volume,
decreased compact bone volume,
decreased exploration in new environment,
decreased locomotor activity,
decreased trabecular bone volume,
[+]
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.