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Summary Expression Phenotypes Gene Literature (17) GO Terms (9) Nucleotides (59) Proteins (33) Interactants (111) Wiki
XB-GENEPAGE-920262

tirap     toll-interleukin 1 receptor (TIR) domain containing adaptor protein

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: tirap assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (10 sources): abnormal dendritic cell physiology, abnormal level of surface class II molecules, abnormal macrophage physiology, abnormal response to cardiac infarction, decreased B cell proliferation, decreased IgG3 level, decreased interleukin-12b secretion, decreased interleukin-6 secretion, decreased tumor necrosis factor secretion, increased sensitivity to induced morbidity/mortality