Cafe-au-lait spot, Carcinoid tumor, Chondrocalcinosis, Coarse facial features, Confetti-like hypopigmented macules, Diarrhea, Elevated circulating growth hormone concentration, Elevated circulating parathyroid hormone level, Episodic abdominal pain, Erythema, Extrahepatic cholestasis, Fasting hyperinsulinemia, Frontal bossing, Galactorrhea, Generalized osteoporosis, Glucagonoma, Hypercalcemia, Hypercalciuria, Hyperhidrosis, Hyperinsulinemic hypoglycemia, Hyperparathyroidism, Hyperphosphaturia, Hypertrophic cardiomyopathy, Hypoglycemia, Hypophosphatemia, Increased circulating cortisol level, Increased circulating prolactin concentration, Increased glucagon level, Increased serum insulin-like growth factor 1, Increased urinary cortisol level, Infantile hypercalcemia, Insulinoma, Large hands, Left ventricular hypertrophy, Long foot, Mandibular prognathia, Multiple lipomas, Nephrocalcinosis, Neuroendocrine neoplasm, Osteopenia, Pancreatic islet cell adenoma, Parathyroid adenoma, Parathyroid hyperplasia, Peptic ulcer, Pituitary adenoma, Pituitary corticotropic cell adenoma, Pituitary growth hormone cell adenoma, Pituitary null cell adenoma, Pituitary prolactin cell adenoma, Premature pubarche, Primary hyperparathyroidism, Proportionate tall stature, Renal insufficiency, Subcutaneous lipoma, Tall stature, Thymoma, Thyroid adenoma, Type II diabetes mellitus, Zollinger-Ellison syndrome, obsolete Prolactinoma

embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, homeostasis/metabolism phenotype, increased Leydig cell tumor incidence, increased adrenal cortical tumor incidence, increased adrenal gland adenoma incidence, increased adrenal gland tumor incidence, increased adrenocortical adenoma incidence, increased gastrointestinal tumor incidence, increased gland tumor incidence, increased glucagonoma incidence, increased gonad tumor incidence, increased insulinoma incidence, increased intestinal adenoma incidence, increased lung tumor incidence, increased mammary gland tumor incidence, increased pancreas adenoma incidence, increased pancreatic beta cell number, increased pancreatic islet cell adenoma incidence, increased pancreatic islet cell carcinoma incidence, increased parathyroid adenoma incidence, increased parathyroid gland tumor incidence, increased pituitary adenohypophysis tumor incidence, increased pituitary adenoma incidence, increased pituitary gland tumor incidence, increased prolactinoma incidence, increased stomach tumor incidence, increased testis tumor incidence, increased thyroid adenoma incidence, increased thyroid carcinoma incidence, increased thyroid tumor incidence, increased tumor incidence, lethality throughout fetal growth and development, complete penetrance, pancreas necrosis, pancreatic islet hyperplasia, premature death, thin interventricular septum, thin ventricular wall, thyroid gland cyst, trabecula carnea hypoplasia