| Monarch Ortholog Phenotypes
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Human (3 sources):
Compensated hemolytic anemia,
Heinz bodies,
Neonatal hyperbilirubinemia
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Mouse (29 sources):
abnormal catalase activity,
abnormal cell morphology,
abnormal epididymis morphology,
abnormal ileum crypts of Lieberkuhn morphology,
abnormal jejunum crypts of Lieberkuhn morphology,
abnormal lipid level,
abnormal mitochondrial physiology,
abnormal response to injury,
brain ischemia,
cellular necrosis,
cochlear ganglion degeneration,
cochlear inner hair cell degeneration,
cochlear outer hair cell degeneration,
decreased cell proliferation,
decreased cellular sensitivity to gamma-irradiation,
decreased glutathione peroxidase activity,
decreased myocardial infarct size,
enlarged epididymis,
immune system phenotype,
increased cardiac muscle contractility,
increased cellular sensitivity to hydrogen peroxide,
increased cellular sensitivity to oxidative stress,
increased cerebral infarct size,
increased glutathione peroxidase activity,
increased neuron apoptosis,
increased or absent threshold for auditory brainstem response,
increased susceptibility to ischemic brain injury,
increased susceptibility to noise-induced hearing loss,
oxidative stress
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.