ackr3 Phenotypes

Phenotypes

XB-GENEPAGE-939860

Gene Symbol: ackr3 Gene Name: atypical chemokine receptor 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ackr3 assayed (6 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (31 sources): abnormal aortic valve morphology, abnormal atrial thrombosis, abnormal atrioventricular cushion morphology, abnormal cardiac outflow tract development, abnormal heart and great artery attachment, abnormal myocardial fiber morphology, abnormal semilunar valve morphology, cardiac fibrosis, cardiac hypertrophy, decreased grip strength, decreased marginal zone B cell number, decreased survivor rate, decreased total retina thickness, digestive/alimentary phenotype, dilated heart atrium, enlarged myocardial fiber, heart hyperplasia, hematopoietic system phenotype, immune system phenotype, myocardial fiber degeneration, myocardial fiber disarray, neonatal lethality, complete penetrance, neonatal lethality, incomplete penetrance, nervous system phenotype, perinatal lethality, complete penetrance, perinatal lethality, incomplete penetrance, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, complete penetrance, thick aortic valve, thick pulmonary valve [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (31 sources): abnormal aortic valve morphology, abnormal atrial thrombosis, abnormal atrioventricular cushion morphology, abnormal cardiac outflow tract development, abnormal heart and great artery attachment, abnormal myocardial fiber morphology, abnormal semilunar valve morphology, cardiac fibrosis, cardiac hypertrophy, decreased grip strength, [+]