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XB-GENEPAGE-948100
folr1 folate receptor alpha
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal neural tube closure (4 sources), abnormally open neural tube (3 sources), abnormal apical constriction (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: folr1 manipulated (2 sources) |
| Computed annotations: folr1 assayed (1 source) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| neural tube defect (5AP sources, 1 EP source) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + folr1 MO (5 sources), Xla Wt + folr1 MO2 (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (4 sources): Developmental regression, Intellectual disability, Neurodegeneration, Seizure |
| Mouse (39 sources): abnormal allantois morphology, abnormal chorioallantoic fusion, abnormal crypts of Lieberkuhn morphology, abnormal embryo size, abnormal embryo turning, abnormal embryonic neuroepithelial layer differentiation, abnormal folic acid level, abnormal forebrain development, abnormal hindbrain development, abnormal kidney morphology, [+] |
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View all ortholog results at Monarch |