ntf3 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (31)

XB-GENEPAGE-949538

Gene Symbol: ntf3 Gene Name: neurotrophin 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ntf3 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (86 sources): L4 dorsal root ganglion hypertrophy, L5 dorsal root ganglion hypertrophy, abnormal Merkel's receptor morphology, abnormal atrioventricular valve morphology, abnormal atrium myocardial trabeculae morphology, abnormal cerebellar foliation, abnormal cerebellar granule layer morphology, abnormal cranial ganglia morphology, abnormal cutaneous/subcutaneous mechanoreceptor morphology, abnormal dorsal root ganglion morphology, abnormal estrous cycle, abnormal food intake, abnormal heart development, abnormal heart left ventricle size, abnormal heart ventricle outflow tract morphology, abnormal innervation, abnormal innervation pattern to muscle, abnormal keratinocyte morphology, abnormal limb posture, abnormal mechanoreceptor morphology, abnormal motor capabilities/coordination/movement, abnormal muscle spindle morphology, abnormal nervous system tract morphology, abnormal noradrenaline level, abnormal proprioceptive neuron morphology, abnormal semilunar valve morphology, abnormal sensory capabilities/reflexes/nociception, abnormal sensory ganglion morphology, abnormal sensory neuron innervation pattern, abnormal sensory neuron morphology, abnormal sinus venosus morphology, abnormal stellate ganglion morphology, abnormal suckling behavior, abnormal sympathetic ganglion morphology, abnormal vestibulocochlear ganglion morphology, absent golgi tendon organ, absent muscle spindles, absent proprioceptive neurons, atrium myocardium hypoplasia, cardiac hypertrophy, cochlear ganglion hypoplasia, decreased CNS synapse formation, decreased body size, decreased locomotor activity, decreased motor neuron number, decreased neuron number, decreased sensory neuron number, decreased spinal cord size, decreased survivor rate, dilated heart atrium, growth/size/body region phenotype, heart right ventricle outflow tract stenosis, hunched posture, hyperinnervation of Merkel's receptor, hyperinnervation of hair guard cells, hyperinnervation of hair-tylotrich cells, impaired limb coordination, increased Merkel's receptor number, increased heart right ventricle size, limb grasping, muscular atrophy, neonatal lethality, incomplete penetrance, nervous system phenotype, no abnormal phenotype detected, perinatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature closure of the ductus arteriosus, pulmonary alveolar hemorrhage, sinus venosus hypoplasia, small L4 dorsal root ganglion, small L5 dorsal root ganglion, small cochlear ganglion, small dorsal root ganglion, small geniculate ganglion, small mesencephalic trigeminal nucleus, small nodose ganglion, small petrosal ganglion, small superior cervical ganglion, small trigeminal ganglion, superior cervical ganglion hypertrophy, thick aortic valve cusps, thick mitral valve cusps, thick pulmonary valve cusps, trigeminal ganglion hypertrophy, vascular smooth muscle hypotrophy [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (86 sources): L4 dorsal root ganglion hypertrophy, L5 dorsal root ganglion hypertrophy, abnormal Merkel's receptor morphology, abnormal atrioventricular valve morphology, abnormal atrium myocardial trabeculae morphology, abnormal cerebellar foliation, abnormal cerebellar granule layer morphology, abnormal cranial ganglia morphology, abnormal cutaneous/subcutaneous mechanoreceptor morphology, abnormal dorsal root ganglion morphology, [+]