| Monarch Ortholog Phenotypes
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Human (28 sources):
Arthritis,
Asthma,
Autoimmune hemolytic anemia,
Autoimmunity,
Bronchiectasis,
Chronic diarrhea,
Chronic lung disease,
Clubbing of fingers,
Colitis,
Conjunctivitis,
Decreased circulating IgA level,
Decreased circulating antibody level,
Decreased circulating total IgM,
Diarrhea,
Failure to thrive,
Gastritis,
Growth delay,
Hypothyroidism,
Immunodeficiency,
Inflammation of the large intestine,
Lymphadenopathy,
Neutropenia,
Pancytopenia,
Pneumonia,
Recurrent infections,
Recurrent otitis media,
Recurrent sinusitis,
Thrombocytopenia
[+]
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Mouse (14 sources):
abnormal blood urea nitrogen level,
abnormal circulating alkaline phosphatase level,
abnormal circulating amylase level,
abnormal ear position,
absent pinna reflex,
decreased red blood cell distribution width,
decreased susceptibility to graft versus host disease,
impaired natural killer cell mediated cytotoxicity,
increased circulating alkaline phosphatase level,
increased circulating amylase level,
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.