| Monarch Ortholog Phenotypes
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Human (50 sources):
Abnormal anterior chamber morphology,
Abnormal nasal morphology,
Abnormal pinna morphology,
Abnormal vertebral morphology,
Abnormality of the vertebral column,
Bilateral cryptorchidism,
Blepharophimosis,
Broad forehead,
Broad philtrum,
Caudal appendage,
Cleft palate,
Cleft upper lip,
Craniosynostosis,
Cryptorchidism,
Depressed nasal tip,
Diastasis recti,
Downslanted palpebral fissures,
Downturned corners of mouth,
Epicanthus inversus,
Failure to thrive,
Global developmental delay,
Hearing impairment,
Highly arched eyebrow,
Hip dislocation,
Horseshoe kidney,
Hyperlordosis,
Hypertelorism,
Hypoplasia of the musculature,
Hypospadias,
Intellectual disability,
Joint hypermobility,
Large fleshy ears,
Limited elbow movement,
Limited pronation/supination of forearm,
Low-set ears,
Orofacial cleft,
Partial abdominal muscle agenesis,
Prominence of the premaxilla,
Prominent coccyx,
Prominent nasal bridge,
Ptosis,
Radioulnar synostosis,
Scoliosis,
Spina bifida occulta,
Strabismus,
Supernumerary nipple,
Telecanthus,
Torticollis,
Umbilical hernia,
Wide nasal bridge
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Mouse (4 sources):
abnormal blood urea nitrogen level,
abnormal complement protein level,
abnormal renal tubule morphology,
decreased susceptibility to kidney reperfusion injury
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.