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XB-GENEPAGE-953071
smc5 structural maintenance of chromosomes 5
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal brain morphology (1 source), abnormal cardiac ventricle morphology (1 source), decreased size of the brain (1 source), decreased size of the cardiac ventricle (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: smc5 manipulated (1 source) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| congenital heart disease (2AP sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xtr Wt + smc5 CRISPR (3 sources) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (11 sources): abnormal cell differentiation, abnormal mitosis, abnormal mitotic spindle assembly checkpoint, abnormal mitotic spindle morphology, abnormal vibrissa morphology, cellular phenotype, decreased circulating glucose level, increased cell death, increased mitotic index, mitotic nondisjunction, [+] |