| Monarch Ortholog Phenotypes
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Human (8 sources):
Abnormal axonemal organization of respiratory motile cilia,
Abnormal sperm head morphology,
Absent sperm flagella,
Coiled sperm flagella,
Male infertility,
Oligospermia,
Reduced sperm motility,
Tapered sperm head
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Mouse (11 sources):
abnormal sperm axoneme morphology,
abnormal sperm flagellum morphology,
absent sperm flagellum,
coiled sperm flagellum,
decreased circulating fructosamine level,
embryonic lethality prior to tooth bud stage,
immotile sperm,
preweaning lethality, complete penetrance,
reproductive system phenotype,
short sperm flagellum,
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.