| Monarch Ortholog Phenotypes
|
Human (22 sources):
Abnormality of the diaphragm,
Adducted thumb,
Ankylosis,
Anteverted nares,
Congenital contracture,
Decreased fetal movement,
Depressed nasal bridge,
Hypertelorism,
Intrauterine growth retardation,
Low-set ears,
Micrognathia,
Myopathy,
Polyhydramnios,
Preeclampsia,
Pulmonary hypoplasia,
Scoliosis,
Short umbilical cord,
Talipes equinovarus,
Thin upper lip vermilion,
Triangular face,
Ulnar deviation of the hand,
Ulnar deviation of the hand or of fingers of the hand
[+]
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Mouse (22 sources):
abnormal Schwann cell morphology,
abnormal axon fasciculation,
abnormal axon morphology,
abnormal axon radial sorting,
abnormal cochlear nerve morphology,
abnormal endocardium morphology,
abnormal fetal cardiomyocyte morphology,
abnormal mitochondrial crista morphology,
abnormal sciatic nerve morphology,
cardiovascular system phenotype,
decreased body size,
dilated heart ventricle,
embryonic lethality during organogenesis, complete penetrance,
impaired limb coordination,
increased triglyceride level,
joint contracture,
myocardial trabeculae hypoplasia,
pericardial edema,
prenatal lethality, incomplete penetrance,
preweaning lethality, complete penetrance,
thin myocardium,
thin ventricular wall
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.