cnot7 Phenotypes

XB-GENEPAGE-969323

Gene Symbol: cnot7 Gene Name: CCR4-NOT transcription complex subunit 7

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cnot7 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (19 sources): abnormal Sertoli cell morphology, abnormal gametogenesis, abnormal male germ cell apoptosis, abnormal sperm flagellum morphology, abnormal sperm head morphology, abnormal sperm mitochondrial sheath morphology, abnormal spermatid morphology, asthenozoospermia, decreased Sertoli cell number, decreased anxiety-related response, decreased locomotor activity, decreased male germ cell number, decreased testis weight, increased bone mineral content, increased lean body mass, increased red blood cell distribution width, multinucleated giant male germ cells, seminiferous tubule degeneration, small seminiferous tubules [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (19 sources): abnormal Sertoli cell morphology, abnormal gametogenesis, abnormal male germ cell apoptosis, abnormal sperm flagellum morphology, abnormal sperm head morphology, abnormal sperm mitochondrial sheath morphology, abnormal spermatid morphology, asthenozoospermia, decreased Sertoli cell number, decreased anxiety-related response, [+]