ubr4 Phenotypes

Phenotypes

XB-GENEPAGE-970439

Gene Symbol: ubr4 Gene Name: ubiquitin protein ligase E3 component n-recognin 4

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ubr4 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (28 sources): abnormal atrioventricular cushion morphology, abnormal autophagy, abnormal cell death, abnormal fourth ventricle morphology, abnormal heart development, abnormal lateral ganglionic eminence morphology, abnormal liver vasculature morphology, abnormal medial ganglionic eminence morphology, abnormal placental labyrinth vasculature morphology, abnormal vitelline vascular remodeling, abnormal vitelline vasculature morphology, decreased birth body size, decreased brain size, decreased embryo size, dilated liver sinusoidal spaces, embryo phenotype, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, embryonic lethality prior to tooth bud stage, increased cell proliferation, lethality throughout fetal growth and development, complete penetrance, liver hypoplasia, neonatal lethality, complete penetrance, pale yolk sac, preweaning lethality, complete penetrance, thin placenta labyrinth, thin ventricular wall [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (28 sources): abnormal atrioventricular cushion morphology, abnormal autophagy, abnormal cell death, abnormal fourth ventricle morphology, abnormal heart development, abnormal lateral ganglionic eminence morphology, abnormal liver vasculature morphology, abnormal medial ganglionic eminence morphology, abnormal placental labyrinth vasculature morphology, abnormal vitelline vascular remodeling, [+]