usp14 Phenotypes

Phenotypes

XB-GENEPAGE-971841

Gene Symbol: usp14 Gene Name: ubiquitin specific peptidase 14

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: usp14 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (40 sources): Purkinje cell degeneration, abnormal brain commissure morphology, abnormal cerebellar granule cell morphology, abnormal cingulum morphology, abnormal dentate gyrus morphology, abnormal hippocampus pyramidal cell morphology, abnormal lumbar vertebrae morphology, abnormal mechanical nociception, abnormal miniature endplate potential, abnormal neuromuscular synapse morphology, abnormal neurotransmitter secretion, abnormal pons morphology, abnormal pontine nuclei morphology, abnormal spinal cord white matter morphology, abnormal spinal nerve morphology, axonal dystrophy, behavior/neurological phenotype, decreased body size, decreased corpus callosum size, decreased hippocampal commissure size, decreased midbrain size, decreased paired-pulse facilitation, decreased post-tetanic potentiation, homeostasis/metabolism phenotype, impaired synaptic plasticity, increased neuron apoptosis, increased synaptic depression, limb grasping, muscle degeneration, muscle phenotype, muscular atrophy, nervous system phenotype, perinatal lethality, complete penetrance, premature death, preweaning lethality, complete penetrance, reduced long term potentiation, short lumbar vertebrae, small cerebellum, small hippocampus, weakness [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (40 sources): Purkinje cell degeneration, abnormal brain commissure morphology, abnormal cerebellar granule cell morphology, abnormal cingulum morphology, abnormal dentate gyrus morphology, abnormal hippocampus pyramidal cell morphology, abnormal lumbar vertebrae morphology, abnormal mechanical nociception, abnormal miniature endplate potential, abnormal neuromuscular synapse morphology, [+]