| Monarch Ortholog Phenotypes
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Human (21 sources):
Abnormal cerebral vascular morphology,
Abnormality of skin pigmentation,
Abnormality of the nervous system,
Abnormality of the orbital region,
Aplasia/Hypoplasia of the skin,
Cerebral palsy,
Cerebral venous thrombosis,
Deep venous thrombosis,
Gangrene,
Global developmental delay,
Hypercoagulability,
Pulmonary embolism,
Purpura,
Reduced protein C activity,
Seizure,
Superficial thrombophlebitis,
Thin skin,
Venous insufficiency,
Venous thrombosis,
Vitreous hemorrhage,
Warfarin-induced skin necrosis
[+]
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Mouse (10 sources):
abnormal blood coagulation,
abnormal brain thrombosis,
abnormal cardiac thrombosis,
abnormal innate immunity,
abnormal lung thrombosis,
abnormal suckling behavior,
bruising,
focal hepatic necrosis,
neonatal lethality, complete penetrance,
perinatal lethality, complete penetrance
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.