erap1 Phenotypes

Phenotypes

XB-GENEPAGE-983343

Gene Symbol: erap1 Gene Name: endoplasmic reticulum aminopeptidase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: erap1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (14 sources): abnormal CD8-positive, alpha-beta T cell physiology, abnormal antigen presentation, abnormal antigen presentation via MHC class I, abnormal bone mineralization, abnormal cytotoxic T cell physiology, abnormal lymphocyte physiology, abnormal response to infection, decreased T cell proliferation, decreased bone mineral content, decreased interferon-gamma secretion, decreased level of surface class I molecules, immune system phenotype, increased heart weight, increased level of surface class I molecules [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (14 sources): abnormal CD8-positive, alpha-beta T cell physiology, abnormal antigen presentation, abnormal antigen presentation via MHC class I, abnormal bone mineralization, abnormal cytotoxic T cell physiology, abnormal lymphocyte physiology, abnormal response to infection, decreased T cell proliferation, decreased bone mineral content, decreased interferon-gamma secretion, [+]