Diarrhea, Dry skin, Elevated circulating thyroid-stimulating hormone concentration, Fatigue, Feeding difficulties, Global developmental delay, Goiter, Growth delay, Hand tremor, Hoarse cry, Hyperactivity, Hyperemesis gravidarum, Hypersomnia, Hyperthyroidism, Hypothyroidism, Hypotonia, Intellectual disability, Intellectual disability, severe, Jaundice, Large fontanelles, Macroglossia, Motor delay, Muscle weakness, Premature birth, Proptosis, Short stature, Sleep disturbance, Small for gestational age, Tachycardia, Thyroid agenesis, Thyroid hyperplasia, Thyroid hypoplasia, Thyrotoxicosis with diffuse goiter, Umbilical hernia, Weight loss

abnormal thyroid follicle morphology, abnormal thyroid hormone level, abnormal uterine environment, absent estrous cycle, circling, deafness, decreased b-wave amplitude, decreased body length, decreased body size, decreased bone mineral density of femur, decreased bone volume, decreased circulating levels of thyroid hormone, decreased circulating progesterone level, decreased circulating thyroxine level, decreased cochlear outer hair cell number, decreased dopaminergic neuron number, decreased femur compact bone thickness, decreased outer hair cell stereocilia number, decreased ovulation rate, decreased thyroxine level, delayed bone ossification, delayed endochondral bone ossification, impaired adaptive thermogenesis, impaired luteinization, increased circulating thyroid-stimulating hormone level, increased or absent threshold for auditory brainstem response, increased pro-B cell number, increased thyroid-stimulating hormone level, increased thyrotroph cell number, iodide oxidation defect, lethality at weaning, complete penetrance, lethality at weaning, incomplete penetrance, maternal effect, premature death, prenatal lethality, incomplete penetrance, proportional dwarf, reduced female fertility, reduced fertility, reduced male fertility, reproductive system phenotype, small thyroid gland, unidirectional circling