adam19 Phenotypes

Phenotypes

XB-GENEPAGE-993484

Gene Symbol: adam19 Gene Name: ADAM metallopeptidase domain 19

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally localised myoblast (1 source), abnormally localised nucleus in myoblast (1 source), decreased cell migration in cranial neural crest (1 source), decreased muscle cell differentiation (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: adam19 manipulated (7 sources), adam19 assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + adam19 MO (4 sources), Xla Wt + adam19 MO (3 sources), Xla Wt + adam19 MO (1 source), Xla Wt + adam19 MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources): abnormal aortic valve morphology, abnormal atrioventricular cushion morphology, abnormal cardiac outflow tract development, abnormal mitral valve morphology, abnormal skeletal muscle morphology, abnormal vascular endothelial cell morphology, abnormal vascular smooth muscle morphology, decreased atrioventricular cushion size, heart right ventricle aneurysm, postnatal lethality, incomplete penetrance, pregnancy-related premature death, skeleton phenotype, thick aortic valve, thick aortic valve cusps, thick pulmonary valve cusps, thick tricuspid valve, thin diaphragm muscle [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (17 sources): abnormal aortic valve morphology, abnormal atrioventricular cushion morphology, abnormal cardiac outflow tract development, abnormal mitral valve morphology, abnormal skeletal muscle morphology, abnormal vascular endothelial cell morphology, abnormal vascular smooth muscle morphology, decreased atrioventricular cushion size, heart right ventricle aneurysm, postnatal lethality, incomplete penetrance, [+]