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XB-GENEPAGE-993757
capn2 calpain 2
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal cardiac ventricle morphology (2 sources), decreased size of the heart (2 sources) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Computed annotations: capn2 assayed (1 source) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| hypoplastic left heart syndrome (2AP sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + capn2 CRISPR + GFP (1 source), Xla Wt + capn2 MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (9 sources): abnormal preimplantation embryo development, abnormal survival, abnormal vascular development, embryonic lethality before implantation, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, pale placenta, prenatal lethality, complete penetrance, thin ventricular wall, transmission ratio distortion |