clpb Phenotypes

Phenotypes

XB-GENEPAGE-994912

Gene Symbol: clpb Gene Name: ClpB family mitochondrial disaggregase

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: clpb assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (42 sources): 3-Methylglutaconic aciduria, Abnormal facial shape, Abnormal pyramidal sign, Abnormality of extrapyramidal motor function, Abnormality of the basal ganglia, Bone marrow hypocellularity, Cardiomyopathy, Cataract, Cerebellar atrophy, Cerebral atrophy, Choreoathetosis, Delayed gross motor development, Developmental regression, Elevated circulating hepatic transaminase concentration, Encephalopathy, Feeding difficulties, Global developmental delay, Growth delay, Hepatic steatosis, Hyperreflexia, Hypothyroidism, Hypotonia, Increased circulating lactate concentration, Infection associated neutropenia, Intellectual disability, Microcephaly, Myoclonus, Neonatal hypoglycemia, Neonatal hypotonia, Nephrocalcinosis, Neutropenia, Nystagmus, Opisthotonus, Pneumothorax, Primary microcephaly, Progressive extrapyramidal movement disorder, Recurrent infections, Renal cyst, Renal insufficiency, Respiratory insufficiency, Seizure, Spasticity [+]
View all ortholog results at Monarch

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Human (42 sources): 3-Methylglutaconic aciduria, Abnormal facial shape, Abnormal pyramidal sign, Abnormality of extrapyramidal motor function, Abnormality of the basal ganglia, Bone marrow hypocellularity, Cardiomyopathy, Cataract, Cerebellar atrophy, Cerebral atrophy, [+]