crb3 Phenotypes

XB-GENEPAGE-995123

Gene Symbol: crb3 Gene Name: crumbs 3, cell polarity complex component

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: crb3 assayed (3 sources)
Computed annotations: crb3 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources): abnormal club cell morphology, abnormal kidney epithelium morphology, abnormal lung epithelium morphology, abnormal proximal convoluted tubule brush border morphology, abnormal pulmonary alveolus morphology, abnormal pulmonary alveolus wall morphology, abnormal respiratory conducting tube morphology, abnormal small intestinal microvillus morphology, decreased small intestinal microvillus size, dilated renal tubules, fused small intestinal villi, impaired mucociliary clearance, neonatal lethality, complete penetrance, no abnormal phenotype detected, perinatal lethality, complete penetrance, preweaning lethality, complete penetrance, small kidney [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (17 sources): abnormal club cell morphology, abnormal kidney epithelium morphology, abnormal lung epithelium morphology, abnormal proximal convoluted tubule brush border morphology, abnormal pulmonary alveolus morphology, abnormal pulmonary alveolus wall morphology, abnormal respiratory conducting tube morphology, abnormal small intestinal microvillus morphology, decreased small intestinal microvillus size, dilated renal tubules, [+]