ptgs1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-995314

Gene Symbol: ptgs1 Gene Name: prostaglandin-endoperoxide synthase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: ptgs1 assayed (1 source)
Computed annotations: ptgs1 assayed (5 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (47 sources): abnormal blood coagulation, abnormal blood flow velocity, abnormal circadian regulation of heart rate, abnormal circadian regulation of systemic arterial blood pressure, abnormal corpus luteum morphology, abnormal keratinocyte differentiation, abnormal kidney morphology, abnormal nociception after inflammation, abnormal response of heart to induced stress, abnormal response/metabolism to endogenous compounds, abnormal small intestine crypts of Lieberkuhn morphology, abnormal stomach pH, abnormal thromboxane level, abnormal uterine environment, abnormal wound healing, behavior/neurological phenotype, cardiovascular system phenotype, decreased brain blood flow rate, decreased digestive secretion, decreased physiological sensitivity to xenobiotic, decreased prostaglandin level, decreased susceptibility to induced arthritis, decreased susceptibility to induced thrombosis, decreased urine prostaglandin level, delayed parturition, digestive/alimentary phenotype, growth/size/body region phenotype, homeostasis/metabolism phenotype, increased bronchoconstrictive response, increased cellular sensitivity to gamma-irradiation, increased circulating progesterone level, increased mean systemic arterial blood pressure, increased prostaglandin level, increased renal glomerular filtration rate, increased renal vascular resistance, increased sensitivity to xenobiotic induced morbidity/mortality, increased small intestinal crypt cell apoptosis, increased susceptibility to endotoxin shock, increased susceptibility to induced colitis, increased susceptibility to injury, increased thermal nociceptive threshold, maternal effect, muscle phenotype, nervous system phenotype, perinatal lethality, incomplete penetrance, reproductive system phenotype, skeleton phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (47 sources): abnormal blood coagulation, abnormal blood flow velocity, abnormal circadian regulation of heart rate, abnormal circadian regulation of systemic arterial blood pressure, abnormal corpus luteum morphology, abnormal keratinocyte differentiation, abnormal kidney morphology, abnormal nociception after inflammation, abnormal response of heart to induced stress, abnormal response/metabolism to endogenous compounds, [+]