c3ar1 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-995350

Gene Symbol: c3ar1 Gene Name: complement C3a receptor 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal superficial layer of neurectoderm (2 sources), abnormally delayed closure of blastopore (1 source), abnormally increased number of cell (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: c3ar1 assayed (16 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + c3ar1 MO (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (37 sources): abnormal T-helper 2 cell differentiation, abnormal T-helper 2 physiology, abnormal adaptive immunity, abnormal c-wave shape, abnormal eosinophil physiology, abnormal fat pad morphology, abnormal grip strength, abnormal interleukin level, abnormal kidney morphology, abnormal lean body mass, abnormal respiratory mucosa goblet cell morphology, abnormal retina horizontal cell morphology, abnormal retina rod bipolar cell morphology, abnormal seminal vesicle morphology, decreased IgG1 level, decreased a-wave amplitude, decreased airway responsiveness, decreased b-wave amplitude, decreased circulating free fatty acids level, decreased circulating interleukin-6 level, decreased circulating phospholipid level, decreased eosinophil cell number, decreased grip strength, decreased interleukin-4 secretion, decreased osteoclast cell number, decreased retina inner nuclear layer thickness, decreased susceptibility to experimental autoimmune encephalomyelitis, disorganized retina outer nuclear layer, hematopoietic system phenotype, impaired liver regeneration, impaired neutrophil recruitment, increased circulating interleukin-1 beta level, increased retina apoptosis, increased sensitivity to induced morbidity/mortality, increased susceptibility to endotoxin shock, increased susceptibility to type I hypersensitivity reaction, thin retina outer nuclear layer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (37 sources): abnormal T-helper 2 cell differentiation, abnormal T-helper 2 physiology, abnormal adaptive immunity, abnormal c-wave shape, abnormal eosinophil physiology, abnormal fat pad morphology, abnormal grip strength, abnormal interleukin level, abnormal kidney morphology, abnormal lean body mass, [+]